Chapter 4 92 Table 4.3 - Associations of UPs and current or past psychiatric diagnosis for all maternal and neonatal outcomes. Model 1 without interaction term1 Model 2 with interaction term2 Measure Main effect UP 95% CI P-value (Wald) Main effect PD 95% CI P-value (Wald) Interaction term UP*PD 95% CI P-value (Wald) P-value interaction term (LRT) Maternal outcomes Gestational diabetes mellitus OR 1.11 0.82 – 1.49 0.507 0.77 0.56 – 1.05 0.097 0.64 0.37 – 1.13 0.124 0.124 Hypertensive disorders of pregnancy OR 0.87 0.59 – 1.27 0.492 0.74 0.50 – 1.10 0.140 0.75 0.37 – 1.55 0.439 0.440 Vaginal delivery, assisted OR 0.95 0.60 – 1.49 0.827 0.72 0.44 – 1.16 0.185 0.69 0.29 – 1.62 0.387 0.388 Caesarean section OR 0.82 0.64 – 1.03 0.096 1.18 0.93 – 1.50 0.173 0.70 0.45 – 1.10 0.122 0.123 Neonatal outcomes Gestational age at delivery in days MD 1.05 -1.06-3.17 0.329 0.60 -1.58-2.78 0.592 6.51 2.51-10.51 0.001 0.001 Premature birth (<37 weeks) OR 0.73 0.48 – 1.11 0.144 0.85 0.54 – 1.33 0.492 0.82 0.37 – 1.83 0.618 0.619 Birthweight in grams MD -36.72 -89.99 – 16.56 0.177 -33.45 -88.16 – 21.27 0.231 -0.60 -101.48 – 100.27 0.991 0.991 Birthweight percentile MD -2.64 -5.64 – 0.36 0.085 -1.97 -5.07 – 1.14 0.214 -5.09 -10.80 – 0.62 0.081 0.081 SGA n, % OR 1.22 0.89 – 1.68 0.215 1.06 0.77 – 1.46 0.732 1.07 0.59 – 1.96 0.828 0.828 LGA n, % OR 0.89 0.61 – 1.30 0.546 0.83 0.55 – 1.23 0.349 0.62 0.30 – 1.29 0.200 0.200 5-minute Apgar score MD -0.01 -0.13 – 0.11 0.845 0.05 -0.07 – 0.18 0.397 0.18 -0.05 – 0.41 0.129 0.129 Low Apgar Score (<7 after 5 minutes) OR 1.32 0.67 – 2.54 0.417 1.01 0.47 – 2.15 0.990 0.33 0.09 – 1.20 0.093 0.092 Admission to a neonatal care unit OR 0.92 0.59 – 1.43 0.724 1.23 0.76 – 1.99 0.391 1.22 0.51 – 3.09 0.661 0.659 Breastfeeding OR 1.30 0.93 – 1.83 0.129 0.54 0.37 – 0.78 0.001 1.01 0.49 – 2.02 0.969 0.969 OR, odds ratio; MD, mean difference; UP, unintended pregnancy; PD, current or past psychiatric diagnosis; SGA, small for gestational age; LGA, large for gestational age; CI, confidence interval; LRT, likelihood ratio test. 1Model included main effects of UP and PD, and was adjusted for psychoactive medication use, parity, employment status, age, alcohol use and smoking. 2Model was adjusted for psychoactive medication use, parity, employment status, age, alcohol use, smoking and included the interaction term psychiatric diagnosis*UP.
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