Pregnancy intention in relation to maternal and neonatal outcomes in women with vs without psychiatric diagnoses 85 the mother's parents and grouped according to the Dutch obstetric registration system23. Employment status of the mother was defined as having a paid job (yes/no) at time of conception. We gathered data on smoking and alcohol use during pregnancy, defined as any use of these substances from the moment of conception onward. Parity was defined as being primiparous (never delivered) or multiparous (delivered previously). We collected data on common somatic conditions and other reasons that require hospital pregnancy care: diabetes mellitus, hypertension, thyroid conditions, asthmatic conditions, epilepsy, history of cesarean section, bariatric surgery, obesity, gynecological conditions, and autoimmune diseases. Psychotropic medication use was defined as use of one or more psychotropic drugs during pregnancy. Maternal outcomes Hypertensive disorders of pregnancy (HDP) and gestational diabetes (GDM) were defined in accordance with local guidelines. Deliveries were grouped by spontaneous vaginal delivery, assisted vaginal delivery and cesarean section. Neonatal outcomes Prematurity was defined as gestational age (GA) at delivery <37 weeks. Birthweight percentile was calculated according to the Hoftiezer curve, which includes sex, GA at delivery and birthweight24. Small for gestational age (SGA) was defined as a birthweight <10th percentile and being large for gestational age (LGA) as a birthweight >90th percentile. Apgar scores after 5 min were collected. Low Apgar score was defined as <7 after 5 min25. Admission to the neonatal ward was registered for those neonates in need of pediatric care. In standard care, neonates are admitted to the maternity ward with their mothers in case of absence of pediatric complications. We defined breastfeeding intention as all women who fully or partially breastfed their infants at the moment they left the hospital after delivery. Statistical methods A power analysis indicated a minimum required sample size of 119 participants in both groups of the primary analyses (current/past psychiatric diagnoses and UPs) based on a UP rate of 43%–82% in women with psychiatric diagnosis11. All analyses were conducted in R studio version 4.2.226. For descriptive analyses of normally distributed variables, means and standard deviations were reported. Continuous variables that were not normally distributed were described with median and interquartile range. Categorical variables were reported with numbers and
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