Chapter 2 32 Results per subgroup of psychiatric disorder The results of all individual studies are presented in Table 2.1. UPs in women with a psychiatric disorder versus no psychiatric disorder Three studies compared women with a psychiatric disorder (not specified) to a control group33,37,38. Tenkku et al. found no difference in OR of UPs between women with and without any psychiatric disorder37, while both Micali et al. and Takahashi et al. reported higher ORs in women with a psychiatric condition compared to controls33,38. Mood disorders We found five studies that included women with mood disorders34-38. Hall et al. found similar rates of UPs in young women with and without depressive symptoms in a prospective setting even as Tenkku et al. in cross-sectional analyses34,37. In contrast, Takahashi et al. found a higher OR of UPs in women with mood disorders compared to women without mood disorders38. Two studies without control groups reported prevalences of UPs (85% in Green et al. and 46–48.4% in Roca et al.)35,36. Anxiety disorders Women with various anxiety disorders were included in three studies36-38. Tenkku et al. showed no difference between women with and without anxiety disorder according to DSM-IV (of which most women had a trauma-related disorder) in UPs37. However, Takahashi et al. presented an increased OR of UPs in women with anxiety disorders compared to women without anxiety disorders38. In the study sample of Roca et al., 40 women with panic disorder, 16 with generalized anxiety disorder, 10 with obsessive-compulsive disorder, three with post-traumatic stress disorder and two with anxiety disorder not otherwise specified were included, of which 33 had UPs (46% of women with any type of anxiety disorder)36. Psychosis and related disorders Women with psychosis and related disorders were investigated in two papers35,39. Green et al. described 85% UPs in 39 women with a risk for postpartum psychotic episode (history of psychotic episode, history of postpartum depression or bipolar disorder) who were in care at a perinatal mental health service during their pregnancy35. Gupta et al. compared the incidence of abortions between women with and without schizophrenia in the first year after a previous pregnancy (these pregnancies are referred to as ‘rapid repeat pregnancies’)39 and found similar rates of induced abortions in both groups.
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