Chapter 2 28 Methods A review protocol was developed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement25 and was registered with Prospero (review number CRD42020221072). Information sources and search strategy The electronic databases PubMed, Embase/Ovid, PsycINFO, Cochrane and Web of Science/Clarivate Analytics were searched on November 6, 2020 (see Additional file 1 for search strategy) to identify studies reporting the proportions of UPs in adult women with (and without) psychiatric vulnerability via self-report, structured clinical interviews, or diagnosis performed by a professional. There were no restrictions in publication date applied to the search. Only articles in English language were included. Unpublished studies and abstracts were excluded from the review. Eligibility criteria Presence of psychiatric vulnerability at the time of conception was a prerequisite for inclusion. Also, the main outcome, namely UPs that can result in both ongoing pregnancies and elective (induced) abortions, had to be reported. Studies that evaluated pregnancy planning (planned and unplanned pregnancies) instead of pregnancy intention were also included. Studies with or without ‘control groups’ (women without a psychiatric vulnerability) were included. Study selection Studies were eligible for inclusion if the following criteria were met: - study participants were women who had become pregnant. - participants were adults: 1) age ≥ 18 years, 2) 95% of the participants was ≥18 years old (mean age − 2 standard deviations ≥18), or 3) a subgroup analysis in women ≥18 years was performed. - participants had a psychiatric vulnerability (a history of psychiatric disorders according to DSM-IV or 5 and ICD-10/11 and/or current psychiatric disorder according to DSM-IV or 5 and ICD-10/11) via self-report, structured clinical interviews, or diagnosis performed by a professional. - studies evaluated proportions of unintended, mistimed, unwanted or unplanned pregnancies resulting in ongoing pregnancies or induced abortions. When articles reported unclear in- and exclusion criteria, the authors were contacted to provide this information. In addition, we contacted authors of studies from 01 to
RkJQdWJsaXNoZXIy MTk4NDMw