219 To overcome this gap, the main aim of this thesis was to develop and test a multi-component health literacy intervention to optimize self-management of CKD patients with LHL, and to strengthen the communication between these patients and their healthcare professionals (HCPs). We aimed for an intervention optimizing care in both general practices and nephrology clinics, as those settings are responsible for treating patients in different stages of CKD. First, we identified potential targets and strategies for our health literacy intervention. Second, we developed the multi-component intervention, targeting the barriers of both CKD patients and HCPs. Third, we assessed the effectiveness and costeffectiveness of our intervention.
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