188 137 Supplementary file 6 Analyses for general practices and hospitals separately for the imputed dataset Linear and logistic regressions of primary outcomes for the change between T0-T1 and T0-T2, with imputation and correction for eGFR. Continuous primary outcomes Group Baseline T1 T2 Intervention effect T0-T1 Intervention effect T0-T2 B (95% CI) p B (95% CI) p PAM1 mean (SD) general practices C 55.3 (7.7) 57.0 (14.5) 60.7 (12.0) -2.00 (-13.58 to 9.59) 0.734 -4.52 (-11.87 to 2.84) 0.228 I 61.3 (13.2) 61.9 (18.7) 63.4 (10.4) PAM1 mean (SD) hospitals C 55.8 (11.3) 55.8 (13.9) 57.9 (13.7) 1.57 (-5.25 to 8.38) 0.651 -3.24 (-8.93 to 2.44) 0.264 I 61.9 (13.8) 64.0 (16.5) 61.9 (11.9) Medication adherence2 mean (SD) general practices C 23.7 (1.7) 23.8 (2.0) 23.5 (2.0) -0.49 (-2.55 to 1.58) 0.641 -0.41 (-1.95 to 1.14) 0.603 I 23.8 (1.5) 23.3 (3.2) 23.2 (2.7) Medication adherence2 mean (SD) hospitals C 23.8 (2.2) 23.6 (2.8) 23.6 (2.1) 0.23 (-0.75 to 1.21) 0.647 -0.04 (-1.31 to 1.26) 0.946 I 23.1 (2.5) 23.1 (2.8) 23.2 (2.6) Alcohol (doses per week) mean (SD) general practices C 6.1 (4.6) 5.3 (4.5) 6.6 (5.7) 0.64 (-0.76 to 2.03) 0.370 -1.70 (-4.08 to 0.68) 0.162 I 4.5 (5.7) 4.4 (5.3) 3.5 (5.4) Alcohol (doses per week) mean (SD) hospitals C 6.8 (6.6) 6.2 (5.5) 5.8 (7.0) -0.29 (-3.17 to 2.59) 0.844 -0.58 (-3.66 to 2.50) 0.711 I 4.7 (7.1) 4.1 (4.9) 3.8 (4.9) Salt intake (days per week) mean (SD) general practices C 5.9 (1.7) 5.6 (1.8) 5.6 (1.8) 0.02 (-1.09 to 1.12) 0.977 0.13 (-1.14 to 1.39) 0.841 I 5.0 (2.1) 4.7 (2.1) 4.8 (2.1) Salt intake (days per week) mean (SD) hospitals C 4.6 (1.9) 4.2 (2.2) 4.8 (2.2) -0.02 (-0.86 to 0.82) 0.968 -1.15 (-2.21 to -0.10) 0.032 I 4.8 (1.8) 4.4 (1.9) 4.0 (1.9) Dichotomous primary outcomes Group Baseline T1 T2 OR (95% CI) p OR (95% CI) p Adequate physical activity3 %, general practices C 44.9 38.7 43.2 2.57 (0.63 to 10.56) 0.190 0.78 (0.21 to 3.00) 0.721 I 40.7 49.6 36.6 Adequate physical activity3 %, hospitals C 43.6 36.7 41.8 1.80 (0.50 to 6.47) 0.370 1.31 (0.43 to 3.94) 0.633 I 30.5 37.0 35.0 Drink more than 1.5L a day % general practices C 60.9 57.2 62.8 1.72 (0.37 to 8.11) 0.492 1.04 (0.26 to 4.21) 0.953 I 32.2 50.2 52.0 Drink more than 1.5L a day % hospitals C 64.1 63.5 69.6 1.12 (0.38 to 3.29) 0.837 0.88 (0.28 to 2.74) 0.824 I 58.6 63.7 59.3 Statistics based on the imputed dataset. Numbers in bold indicate significant results. n of alcohol is 39 for GPs and 45 for hospitals (only people who drank were analysed); all other n = 59 for GPs and 88 for hospitals. B = parameter estimate of being in the IG for the difference T1-T0 or T2-T0, CI = confidence interval, SD = standard deviation, CAU = care-as-usual, IG = intervention group, OR = odds ratio for improvement in the IG compared to CAU between baseline and T1 or T2. 1 Patient Activation Measure: scores from 0 to 100 with higher scores representing better patient activation. 2 Medication adherence: scores from 5 to 25 with higher scores representing better adherence. 3 Adequate physical activity: at least 150 minutes of exercise per week. Supplementary file 6: Analyses for general practices and hospitals separately for the imputed dataset
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