186 135 Supplementary file 5 Analyses for patients with limited health literacy for the imputed dataset Linear and logistic regressions of primary outcomes for the change between T0-T1 and T0-T2, with imputation and correction for eGFR. Continuous primary outcomes Group Baseline T1 T2 Intervention effect T0-T1 Intervention effect T0-T2 B (95% CI) p B (95% CI) p PAM1 mean (SD) C 53.7 (9.2) 54.2 (12.8) 56.9 (12.2) 1.04 (-5.49 to 7.57) 0.754 -0.75 (-5.76 to 4.27) 0.771 I 58.8 (11.6) 61.0 (15.9) 62.3 (9.5) Medication adherence2 mean (SD) C 24.1 (1.2) 23.8 (2.0) 23.6 (2.1) 0.11 (-0.91 to 1.13) 0.827 0.23 (-0.82 to 1.27) 0.667 I 23.6 (2.0) 23.4 (2.7) 23.3 (2.5) Alcohol (doses per week) mean (SD) C 5.9 (5.7) 4.9 (4.5) 6.0 (6.8) -0.11 (-2.00 to 1.78) 0.909 -1.83 (-4.30 to 0.64) 0.146 I 5.7 (7.7) 4.7 (5.9) 4.2 (5.9) Salt intake (days per week) mean (SD) C 5.3 (1.8) 4.9 (2.1) 5.3 (2.0) -0.14 (-0.87 to 0.59) 0.704 -0.74 (-1.65 to 0.17) 0.109 I 5.2 (1.9) 4.6 (2.0) 4.4 (2.1) Dichotomous primary outcomes Group Baseline T1 T2 OR (95% CI) p OR (95% CI) p Adequate physical activity3 % C 36.1 31.0 36.2 1.93 (0.66 to 5.65) 0.231 0.66 (0.24 to 1.85) 0.432 I 40.0 43.1 30.3 Drink more than 1.5L a day % C 61.0 58.5 61.7 1.20 (0.47 to 3.06) 0.699 1.20 (0.46 to 3.16) 0.710 I 44.4 53.3 58.2 Statistics based on the imputed dataset, but only participants with LHL were included (a score on the AAHLS ≤25). Numbers in bold indicate significant results. n of alcohol is 57 (only people who drank were analysed); all other n = 102. B = parameter estimate of being in the IG for the difference T1-T0 or T2-T0, CI = confidence interval, SD = standard deviation, CAU = care-as-usual, IG = intervention group, OR = odds ratio for improvement in the IG compared to CAU between baseline and T1 or T2. 1 Patient Activation Measure: scores from 0 to 100 with higher scores representing better patient activation. 2 Medication adherence: scores from 5 to 25 with higher scores representing better adherence. 3 Adequate physical activity: at least 150 minutes of exercise per week. Supplementary file 5: Analyses for patients with limited health literacy for the imputed dataset
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