Marco Boonstra

171 Continuous primary outcomes Group Baseline T1 T2 Intervention effect T0-T1 Intervention effect T0-T2 B (95% CI) p B (95% CI) p PAM1 mean (SD) CAU 55.6 (10.0) 56.3 (14.2) 59.0 (13.1) 0.25 (-5.41 to 5.92) 0.930 -3.90 (-8.25 to 0.46) 0.080 IG 61.7 (13.6) 63.1 (17.5) 62.5 (11.4) Medication adherence2 mean (SD) CAU 23.8 (2.0) 23.7 (2.5) 23.6 (2.1) -0.08 (-1.11 to 0.95) 0.882 -0.05 (-1.05 to 0.96) 0.930 IG 23.4 (2.2) 23.2 (2.9) 23.2 (2.6) Alcohol (doses per week) mean (SD) CAU 6.4 (5.5) 5.7 (5.0) 6.3 (6.3) 0.20 (-1.25 to 1.64) 0.790 -1.07 (-2.84 to 0.70) 0.236 IG 4.6 (6.5) 4.2 (5.1) 3.7 (5.1) Salt intake (days per week) mean (SD) CAU 5.1 (1.9) 4.8 (2.1) 5.1 (2.1) -0.03 (-0.68 to 0.63) 0.939 -0.59 (-1.40 to 0.22) 0.153 IG 4.9 (1.9) 4.5 (2.0) 4.4 (2.0) Dichotomous primary outcomes Group Baseline T1 T2 OR (95% CI) p OR (95% CI) p Adequate physical activity3 % CAU 44.1 37.5 42.4 1.95 (0.78 to 4.84) 0.152 0.98 (0.43 to 2.22) 0.962 IG 34.6 42.1 35.7 Fluid intake of >1.5L a day % CAU 62.8 60.9 66.8 1.25 (0.56 to 2.82) 0.588 0.87 (0.37 to 2.03) 0.748 IG 48.0 58.3 56.4 Table 5.2 Linear and logistic regressions of primary and secondary patient outcomes for the change between T0-T1 and T0-T2, corrected for eGFR Continuous secondary outcomes Group Baseline T1 T2 B (95% CI) P B (95% CI) P Health literacy1 mean (SD) CAU 23.0 (3.1) 23.7 (3.2) 23.6 (3.3) -0.33 (-1.52 to 0.87) 0.593 -0.27 (-1.53 to 0.99) 0.674 IG 23.8 (3.1) 24.0 (3.1) 24.0 (3.4) N of lifestyle topics discussed in CAU 1.5 (1.1) 1.0 (1.2) 1.3 (1.3) 0.80 (0.28 to 1.31) 0.003 0.69 (0.14 to 1.25) 0.014 consultation mean (SD) IG 1.1 (1.3) 1.4 (1.4) 1.5 (1.5) eGFR2 mean (SD) CAU 33.9 (14.9) 32.7 (15.0) -2.39 (-6.01 to 1.23) 0.195 IG 43.3 (16.2) 39.7 (15.4) BMI mean (SD) CAU 28.1 (5.4) 28.3 (5.6) 27.9 (4.9) 0.23 (-1.41 to 1.87) 0.779 0.31 (-1.23 to 1.86) 0.690 IG 27.5 (4.4) 27.9 (5.9) 27.6 (5.1)

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