158 ABSTRACT Background Chronic kidney disease (CKD) patients with limited health literacy (LHL) are at risk for faster disease progression. To counteract, we developed ‘Grip on your Kidneys’ (GoYK), an intervention targeting patients and health care professionals. We assessed the effect on self-management, patient activation, clinical parameters, consultation quality, and the professionals’ use of health literacy strategies. We further evaluated the process. Methods A quasi-experimental study was conducted, including 147 patients with CKD and 48 professionals from Dutch general practices and nephrology clinics. Patients and professionals in the intervention group (IG) received GoYK. Control patients received care-as-usual from the participating professionals. Data were collected with questionnaires and from patient records at baseline (T0), 4 months (T1) and 9 months (T2). Results No effects on self-management and patient activation were found. At T2, the proportion of patients with hypertension decreased in the IG (odds ratio=0.45, 95% confidence interval (95%CI) [0.20, 0.99]). In the IG, more lifestyle topics were discussed, at T1 (difference=0.80, 95%CI [0.28, 1.31]) and T2 (difference=0.69, 95%CI [0.14, 1.25]). Furthermore, several outcomes related to consultation quality improved. Professionals in the IG improved the use of health literacy strategies more, at T1 (difference=0.64, 95%CI [0.33, 0.95]) and T2 (difference=0.56, 95%CI [0.19, 0.93]). In general, patients and professionals considered GoYK to be useful. Conclusions GoYK is promising, and offers a blueprint to optimize care for patients with LHL. Researchers should develop and test interventions like GoYK, focusing on patients at risk for CKD, and with very low health literacy.
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