73 Effectiveness of MRSA decolonization regimens 4 Table 3: Follow-up after decolonization treatment Follow-up cultures after treatment Total treated patients = 131 Week 1 Week 2 Week 3 First decolonization attempt Available Positive 130 14 111 8 103 6 Second decolonization attempt Available Positive 17 2 15 2 13 2 Third decolonization attempt Available Positive 4 0 4 1 3 0 Legend: Follow-up cultures after decolonization treatment. Values are count. After one positive culture, no further follow-up cultures were performed. Table 4: Decolonization success rates of antibiotic regimens Antibiotic agents Treated first attempt Successful after first attempt Treated second attempt Successful after second attempt Treated third attempt Successful after third attempt Doxycycline + rifampicin 37 32 (86%; 71-96) 1 1 0 - Trimethoprim* + rifampicin 60 41 (68%; 55-80) 8 5 3 2 Clindamycin + rifampicin 19 15 (79%; 54-94) 2 1 1 1 Other 15 9 (60%; 32-84) 6 4 0 - Total 131 97 (74%) 17 11 (65%) 4 3 (75%) Legend: Values are count (%; 95% confidence interval). The most frequently used combinations of antibiotic agents are mentioned, the 8 other antibiotic regimens are bundled in ‘other’. *Trimethoprim was with or without sulfamethoxazole. ‘First attempt’ is the first attempt with systemic antibiotic agents added to the treatment, i.e. first treatment episode in complicated colonization or second treatment episode after failure of first treatment with topical treatment in uncomplicated colonization.
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