247 Meta-analysis female sex and mortality in SAB 10 eTable 2. Evidence profile for association of female sex and mortality in patients with Staphylococcus aureus bacteremia. Patient population Patients with Staphylococcus aureus bacteremia Setting Hospital Intervention Female sex Comparison Male sex Outcome Mortality Studies (participants) 89 (132,582) Risk of bias High Consistency Consistent Precision Precise Directness Direct Other limitations Sex-difference was not the primary outcome of interest in the majority of the studies that were included Overall strength of evidence Low Conclusion Female sex is associated with higher mortality in patients with SAB Summary estimate Unadjusted: 1.12 (95%CI 1.07-1.18) Adjusted: 1.18 (95%CI 1.11-1.27)
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