210 Chapter 9 Table S3. Mortality in females and males with S. aureus bacteremia, stratified by MSSA vs MRSA. MSSA MRSA Females N=713 Males N=1085 p Females N=697 Males N=840 p Mortality 30-day 133 (18.7) 186 (17.1) 0.41 166 (23.8) 192 (22.9) 0.67 Mortality 90-day 160 (22.4) 238 (21.9) 0.82 225 (32.3) 250 (29.8) 0.29 Legend. Values are counts (%). Data was missing in <3%. Table S4. Mortality, TEE performance and antibiotic regimen in MSSA bacteremia in females and males with S. aureus bacteremia, stratified by time period. 1994-2002 2003-2011 2012-2020 Females N=497 Males N=630 p Females N=422 Males N=485 p Females N=512 Males N=838 p Mortality 30day 87 (17.5) 91 (14.4) 0.16 82 (19.4) 96 (19.8) 0.93 132 (25.8) 194 (23.2) 0.29 Mortality 90day 122 (24.5) 138 (21.9) 0.32 102 (24.2) 117 (24.1) 1.00 164 (32.0) 236 (28.2) 0.14 TEE performed 179 (36.1) 251 (39.9) 0.20 116 (27.5) 168 (34.6) 0.02 200 (39.1) 383 (45.7) 0.02 Main antibiotic regiment in MSSA 0.08 0.22 0.35 Cefazolin 108 (43.7) 169 (49.0) 60 (33.9) 81 (36.7) 150 (56.6) 274 (55.8) Antistaphylococcal penicillin 48 (19.4) 79 (22.9) 44 (24.9) 67 (30.3) 43 (16.2) 99 (20.2) Otherb 91 (36.8) 97 (28.1) 73 (41.2) 73 (33.0) 72 (27.2) 118 (24.0) Legend. Values are counts (%). Data was missing in <3%. a Pearson Chi-Square tests were used for the analyses. bOther antibiotics used in MSSA bacteremia were mainly vancomycin, ceftriaxone and daptomycin.
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