Annette Westgeest

136 Chapter 6 The following questions refer to treatment duration. How many weeks of antibiotic treatment (includes both IV and oral) would you prescribe in a patient with Staphylococcus aureus bacteremia without implanted prosthetic material and the following foci of infection? 2 weeks 4 weeks 6 weeks >6 weeks Arthritis o o o o Native valve endocarditis o o o o Long bone osteomyelitis o o o o Pneumonia without abscess o o o o Septic thrombophlebitis o o o o Spondylodiscitis without abscess o o o o Would the following factors make you consider extending antibiotic therapy from 2 weeks to 4 weeks in a patient with Staphylococcus aureus bacteremia? Assume transesophageal echocardiography (TEE) does not show signs of endocarditis. Yes No Community-acquisition o o Delay of 48 hours between sampling first positive blood culture and initiation of adequate antibiotic treatment o o Fever at 72 hours after first positive blood culture o o Positive blood cultures after 72 hours of adequate antibiotic treatment o o Unknown portal of entry o o Methicillin resistant Staphylococcus aureus o o Age > 75 years o o Immunocompromised patient o o

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