12 Chapter 1 Despite the high prevalence and global burden of S. aureus, many questions remain unanswered with respect to the management and risk factors of both colonization and invasive infection. Research is continuously ongoing in order to unravel the complexities of this extraordinary pathogen and the diseases it causes in humans. This thesis aims to address the optimization of MRSA decolonization and some of the frequently encountered challenges in S. aureus bacteremia management (Figure 2). Figure 2. Graphical summary of thesis
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