5 88 5. Towards biologically plausible phosphene simulation Figure S9: Results after training an end-to-end model on a small electrode count (60 electrodes) with different interaction conditions. In thebaseline condition, the model was trained without electrode interactions. In the costimulation loss condition, no electrode interactions were simulated, but an additional loss component was introduced to discourage simultaneous activation of neighbouring electrode pairs. In thecoactivation condition, no additional loss function was used, but an interaction model was implemented in the simulator. For each active electrode a coactivation leak current was added from neighbouring electrodes. Left panel: the percentage of active electrode pairs with a relative distance smaller than 1 mm. Costimulation loss resulted in significantly smaller number of active neighbouring electrode pairs. Adding acoactivationcurrent resulted in significant increase of simultaneously active neighbouring electrodes. (p < 0.001 for both comparisons with the baseline condition). Right panel: the coactivation matrix characterizing the magnitude of the leak current between electrodes in thecoactivation condition.
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