Charlotte Poot

168 6 Chapter 6 in SGRQ total score (MD -3.89, 95% CI -6.16 to -1.63) favoured IDM (Analysis 1.2; Figure 3). In other words, those treated with IDM reported 3.89 out of 100 points for improved quality of life. Pooling did indicate considerable heterogeneity (I² = 83%). Sensitivity analysis performed on high-quality studies still showed a statistically signi cant e ect in favour of IDM (MD -3.95, 95% CI -6.06 to -1.84). This e ect was even more pronounced, indicating the robustness of our results. Sensitivity analysis of high-quality studies only did not change the level of heterogeneity (I² = 79%). Pre-de ned and post-hoc subgroup analyses were performed to investigate heterogeneity (see below). Figure 3. Forest plot of comparison: 1 integrated disease management versus control, update, outcome: 1.34 SGRQ total score.

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