Two-year trajectories of COVID-19 symptoms and their association with illness perception: A prospective cohort study in Amsterdam, the Netherlands 6 193 SUPPLEMENTARY MATERIALS Supplementary Materials contain Supplementary Methods, Supplementary Tables S1-S9 and Supplementary Figures S1 and S2. Supplementary Methods. World Health Organization definitions for long COVID and acute COVID-19 severity The WHO long COVID definition was used, namely: reporting ≥1 COVID-19 symptom >3 months after illness onset, and lasting for ≥2 months (i.e., started within one month of overall illness onset)[1]. In an attempt to exclude symptoms secondary to alternative explanations, we considered symptoms commencing >1 month after the onset of COVID-19 unlikely to be due to SARS-CoV-2 infection. COVID-19 severity was categorised according to WHO disease severity criteria[2]: mild disease as having a RR <20/min and SpO2>94% on room air at D0 and D7 study visits; moderate disease as having a RR 2030/min and/or SpO2 90-94% or receiving oxygen therapy at D0 or D7; severe disease as having a RR>30/min and/or SpO2<90% or receiving oxygen therapy at D0 or D7; critical disease as ICU admission due to COVID-19 at any point.
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