Two-year trajectories of COVID-19 symptoms and their association with illness perception: A prospective cohort study in Amsterdam, the Netherlands 6 183 Table 2. Socio-demographic and clinical characteristics of participants per long COVID symptom trajectory group Symptom trajectory number Total 1 2 3 4 p-value N=290* N=70 N=137 N=59 N=24 Baseline socio-demographic and medical characteristics Sex <0.001 Male 169 (58%) 55 (79%) 75 (55%) 33 (56%) 6 (25%) Female 121 (42%) 15 (21%) 62 (45%) 26 (44%) 18 (75%) Age, years 51.0 (36.0-62.0) 46.5 (32.0-64.0) 53.0 (39.0-64.0) 51.0 (41.0-60.0) 51.0 (42.5-55.0) 0.47 BMI category 0.13 Normal weight 121 (42%) 38 (54%) 56 (41%) 20 (34%) 7 (29%) Overweight 101 (35%) 23 (33%) 47 (34%) 21 (36%) 10 (42%) Obese 68 (23%) 9 (13%) 34 (25%) 18 (31%) 7 (29%) Migration background 0.53 Dutch 183 (63%) 45 (64%) 87 (64%) 37 (63%) 14 (58%) Non-Dutch, OECD high-income 31 (11%) 11 (16%) 11 (8%) 7 (12%) 2 (8%) Non-Dutch, OECD low/middle income 69 (24%) 12 (17%) 34 (25%) 15 (25%) 8 (33%) Missing 7 (2%) 2 (3%) 5 (4%) 0 (0%) 0 (0%) Smoking 0.82 Non-smoker 181 (62%) 45 (64%) 83 (61%) 38 (64%) 15 (63%) Smoker 19 (7%) 2 (3%) 11 (8%) 5 (8%) 1 (4%) Ex-smoker 87 (30%) 22 (31%) 41 (30%) 16 (27%) 8 (33%) Missing 3 (1%) 1 (1%) 2 (1%) 0 (0%) 0 (0%) Highest level of education 0.025 None, primary or secondary education 41 (14%) 8 (11%) 24 (18%) 6 (10%) 3 (13%) Vocational training 69 (24%) 10 (14%) 35 (26%) 13 (22%) 11 (46%) University education 172 (59%) 50 (71%) 72 (53%) 40 (68%) 10 (42%) Missing 8 (3%) 2 (3%) 6 (4%) 0 (0%) 0 (0%) Number of COVID-19 high-risk comorbidities 0.73 0 160 (55%) 40 (57%) 76 (55%) 32 (54%) 12 (50%) 1 70 (24%) 17 (24%) 30 (22%) 14 (24%) 9 (38%) 2 36 (12%) 6 (9%) 20 (15%) 7 (12%) 3 (13%) 3 or more 24 (8%) 7 (10%) 11 (8%) 6 (10%) 0 (0%) Follow-up COVID-19-related characteristics Hospital admission 139 (48%) 24 (34%) 69 (50%) 34 (58%) 12 (50%) 0.049 ICU admission 39 (13%) 8 (11%) 20 (15%) 6 (10%) 5 (21%) 0.55 Timing of infection 0.051 First wave 98 (34%) 24 (34%) 51 (37%) 21 (36%) 2 (8%) Subsequent waves 192 (66%) 46 (66%) 86 (63%) 38 (64%) 22 (92%)
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