Chapter 5 158 Table S1b Total Month 6 fatigue survey completed Month 6 survey missing p-value N=267* N=208 N=59 Sex 0.26 Male 153 (57%) 123 (59%) 30 (51%) Female 114 (43%) 85 (41%) 29 (49%) Age, years 49.0 (33.0-62.0) 52.0 (37.0-64.0) 42.0 (27.0-54.0) <0.001 BMI category 0.83 Normal weight 117 (44%) 90 (43%) 27 (46%) Overweight 95 (36%) 74 (36%) 21 (36%) Obese 53 (20%) 43 (21%) 10 (17%) Missing 2 (1%) 1 (0%) 1 (2%) Migration background* 0.005 Dutch 162 (61%) 138 (66%) 24 (41%) Non-Dutch, OECD high-income 35 (13%) 22 (11%) 13 (22%) Non-Dutch, OECD low/middle income 63 (24%) 46 (22%) 17 (29%) Missing 7 (3%) 2 (1%) 5 (8%) Highest level of education 0.68 None, primary or secondary education 36 (13%) 27 (13%) 9 (15%) Vocational training 61 (23%) 47 (23%) 14 (24%) University education 161 (60%) 130 (63%) 31 (53%) Missing 9 (3%) 4 (2%) 5 (8%) Clinical severity score** 0.37 Mild 88 (33%) 70 (34%) 18 (31%) Moderate 120 (45%) 96 (46%) 24 (41%) Severe/critical 59 (22%) 42 (20%) 17 (29%) Number of COVID-19 high-risk comorbidities*** 0.25 0 154 (58%) 119 (57%) 35 (59%) 1 58 (22%) 50 (24%) 8 (14%) 2 30 (11%) 22 (11%) 8 (14%) 3 or more 25 (9%) 17 (8%) 8 (14%) Table presents only participants who have had at least 6 months of follow-up since illness onset; those who are yet to reach this timepoint are not included in the denominator. NA = Not applicable. BMI=Body mass index; OECD= Organisation for Economic Co-operation and Development. Continuous variables presented as median (IQR) and compared using the Kruskal-Wallis test; categorical and binary variables presented as n(%) and compared using the Pearson χ2 test (or Fisher exact test if n<5). * Migration background was based on country of birth of participant and that of their parents and included first and second generation migrants. **Clinical severity groups defined as: mild as having a RR<20/min and SpO2 on room air >94% at both day 0 and 7; moderate disease as having a RR 20-30/min, SpO2 90-94% and/or receiving oxygen therapy at day 0 or 7; severe disease as having a RR>30/min or SpO2 < 90% at day 0 or 7; critical disease as requiring ICU admission. *** COVID-related comorbidities are based on WHO Clinical Management Guidelines[16] and include: cardiovascular disease (including hypertension), chronic pulmonary disease (excluding asthma), renal disease, liver disease, cancer, immunosuppression (excluding HIV, including previous organ transplantation), previous psychiatric illness and dementia.
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