Elke Wynberg

Severe fatigue in the first year following SARS-CoV-2 infection: A prospective cohort study 5 141 Table 1. Socio-demographic, clinical and study characteristics of RECoVERED study participants enrolled between May 2020-August 2021, Amsterdam, the Netherlands, by COVID-19 clinical severity Total Mild COVID-19 Moderate COVID-19 Severe/critical COVID-19 p- value N=303 N=88 N=136 N=79 Socio-demographic features Sex 0.21 Male 173 (57%) 44 (50%) 79 (58%) 50 (63%) Female 130 (43%) 44 (50%) 57 (42%) 29 (37%) Age, years 51.0 (36.0-62.0) 40.0 (27.5-54.5) 49.0 (34.0-60.5) 60.0 (50.0-66.0) <0.001 BMI, kg/m2 26.1 (23.2-29.4) 24.6 (22.8-27.7) 26.2 (23.5-29.4) 27.3 (25.6-32.9) <0.001 BMI category <0.001 Normal weight † 124 (41%) 50 (57%) 56 (41%) 18 (23%) Overweight 106 (35%) 24 (27%) 48 (35%) 34 (43%) Obese 69 (23%) 13 (15%) 32 (24%) 24 (30%) Missing 4 (1%) 1 (1%) 0 (0%) 3 (4%) Migration background (OECD) * 0.001 Dutch 184 (61%) 63 (72%) 78 (57%) 43 (54%) Non-Dutch, OECD HIC 37 (12%) 12 (14%) 21 (15%) 4 (5%) Non-Dutch, OECD LMIC 73 (24%) 10 (11%) 34 (25%) 29 (37%) Missing 9 (3%) 3 (3%) 3 (2%) 3 (4%) Smoking 0.17 Non-smoker 191 (63%) 54 (61%) 81 (60%) 56 (71%) Smoker 20 (7%) 8 (9%) 11 (8%) 1 (1%) Ex-smoker 87 (29%) 23 (26%) 43 (32%) 21 (27%) Missing 5 (2%) 3 (3%) 1 (1%) 1 (1%) Highest level of education <0.001 None, primary or secondary education 42 (14%) 7 (8%) 24 (18%) 11 (14%) Vocational training 73 (24%) 9 (10%) 34 (25%) 30 (38%) University education 178 (59%) 69 (78%) 75 (55%) 34 (43%) Missing 10 (3%) 3 (3%) 3 (2%) 4 (5%) Work situation prior to COVID-19 0.025 Paid employment or self-employed 193 (64%) 64 (73%) 87 (64%) 42 (53%) On sick leave 15 (5%) 0 (0%) 6 (4%) 9 (11%) Retired 37 (12%) 9 (10%) 16 (12%) 12 (15%) Other ** 50 (17%) 14 (16%) 23 (17%) 13 (16%) Missing 8 (3%) 1 (1%) 4 (3%) 3 (4%)

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