101 Microstructures | Syndromic Craniosynostosis Supplemental Table 1. Linear regression on RD Corpus Callosum Genu with independent variables type of syndrome, gender, age, tractvolume and FOHR. Estimate* SE* 2.5% CI* 97.5% CI* P value (Intercept) 0.72 0.15 0.41 1.02 0.000 Apert 0.05 0.07 -0.09 0.20 0.484 Crouzon 0.06 0.05 -0.04 0.17 0.233 Muenke -0.03 0.07 -0.17 0.10 0.609 Saethre-Chotzen -0.03 0.06 -0.15 0.10 0.668 Complex 0.02 0.06 -0.11 0.14 0.806 Gender(female) -0.01 0.03 -0.08 0.06 0.692 Age in years -0.16 0.04 -0.25 -0.07 0.001 Tractvolume in mm3 0 0 0 0 0.093 FOHR per 0.10 0.12 0.03 0.06 0.19 0.001 *all values are x 10^-3 Supplemental Table 2. Linear regression on RD of the hippocampal segment of the left cingulate bundle, with independent variables type of syndrome, gender, age, tractvolume and FOHR. Estimate* SE* 2.5% CI* 97.5% CI* P value (Intercept) 0.79 0.09 0.61 0.97 0.000 Apert 0.00 0.04 -0.09 0.09 0.975 Crouzon 0.02 0.03 -0.04 0.09 0.477 Muenke 0.05 0.04 -0.03 0.13 0.188 Saethre-Chotzen -0.01 0.04 -0.08 0.06 0.779 Complex 0.01 0.04 -0.07 0.08 0.876 Gender(female) 0.00 0.02 -0.04 0.05 0.948 Age in years -0.09 0.03 -0.14 -0.03 0.002 Tractvolume in mm3 0.00 0.00 0.00 0.00 0.597 FOHR per 0.10 0.06 0.02 0.02 0.11 0.002 *all values are x 10^-3 Abbreviations: RD: Radial Diffusivity, FOHR: Frontal Occipital Horn Ratio 6
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