Joëlle Schutten

Contents Chapter 1 General Introduction 9 Chapter 2 Lower plasma magnesium, measured by nuclear magnetic resonance spectroscopy, is associated with increased risk of developing type 2 diabetes mellitus in women: Results from a Dutch prospective cohort study 23 J Clin Med 2019; 8: 169 Chapter 3 Comparison of two methods for the assessment of intraerythrocyte magnesium and its determinants: Results from the LifeLines cohort study 47 Clin Chim Acta 2020; 510: 772-780 Chapter 4 Magnesium and blood pressure: A physiology-based approach 77 Adv Chronic Kidney Dis 2018; 25: 244-250 Chapter 5 Long-term magnesium supplementation improves glucocorticoid metabolism: A post-hoc analysis of an intervention trial 93 Clin Endocrinol 2021; 94 :150–157 Chapter 6 Effects of magnesium citrate, magnesium oxide and magnesium sulfate on arterial stiffness: A randomized double-blind placebocontrolled intervention trial 111 J Am Heart Assoc 2022; 11: e021783 Chapter 7 General Discussion 157 Nederlandse samenvatting 171 Dankwoord 177 About the author 183 List of publications 187

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