80 Chapter 4 Table 4. Recordings >72 hours, including episodes in room air Outcome Oxygenie n=146 CLiO2 n=269 p value* Time SpO2 within target range† % 92.5 [81.8 – 97.2] 90.2 [75.2 – 96.0] 0.005 Time SpO2 below target range % 5.0 [2.2 – 10.6] 6.8 [3.3 – 13.6] 0.003 Time SpO2 above target range‡ % 2.0 [0.7 – 5.9] 2.5 [0.4 – 10.9] n.s. SpO2 85% - 89% % 2.7 [1.1 – 5.3] 3.7 [1.6 – 7.6] 0.002 SpO2 80% - 84% % 0.4 [0.2 – 1.2] 0.8 [0.3 – 1.7] <0.001 SpO2 < 80% % 0.2 [0.1 – 0.5] 0.3 [0.2 – 0.8] <0.001 SpO2 96% - 98% while FiO2 >= 0.24 % 1.7 [0.6 – 5.2] 1.9 [0.3 – 9.0] n.s. SpO2 > 98% while FiO2 >= 0.24 % 0.2 [0.1 – 0.6] 0.4 [0.1 – 1.7] <0.001 Average FiO2 § % 23.0 [21.8 – 25.8] 21.8 [21.1 – 24.8] <0.001 Data in median (IQR). * Kruskal-Wallis test. † 91% <= SpO2 <= 95% or SpO2 >= 96% while FiO2 <= 0.23. ‡ SpO2 >= 96% while FiO2 >= 0.24 . § Average FiO 2 is based on measured FiO2 for OxyGenie and on intended/set FiO2 for CLiO2 Figure 3A. Proportion of time spent within different SpO2 ranges including periods where no supplemental oxygen is administered. Dashed brown line: OxyGenie control, solid blue line: CLiO2 (A): Proportion of time within the 91%-95% range plotted against postnatal age. A
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