Hylke Salverda

Table of contents Preface 8 Part I General introduction Chapter 1 General introduction and outline of this thesis 13 Part II Currently available automated oxygen control algorithms Chapter 2 Automated oxygen control in preterm infants, how does it work and what to expect; a narrative review 27 Part III Effectivity of automated oxygen control algorithms on oxygenation of preterm infants in the NICU Chapter 3 Comparison of two devices for automated oxygen control in preterm infants – a randomised cross-over trial 51 Chapter 4 Comparison of two automated oxygen controllers in oxygen targeting in preterm infants during admission – an observational study 69 Chapter 5 Comparing descriptive statistics for retrospective studies from one-per-minute and one-per-second data 89 Part IV Clinical and long-term outcome after using automated oxygen controllers for preterm infants during NICU stay Chapter 6 The effect of automated oxygen control on clinical outcomes in preterm infants: a pre- and post-implementation cohort study 105 Chapter 7 Automated oxygen control for very preterm infants and neurodevelopmental outcome at two years – a retrospective cohort study 121 Chapter 8 Clinical outcomes of preterm infants while using automated controllers during standard care: comparison of cohorts with different automated titration strategies 137 Part V General discussion and summary Chapter 9 General discussion and future perspectives 153 Chapter 10 Summary 171 Chapter 11 Nederlandse samenvatting 179 Part VI Appendices Affiliations of co-authors 190 Abbreviations 192 List of publications 193 Curriculum Vitae 194 Dankwoord 195