54 Chapter 3 BPD: bronchopulmonary dysplasia, IGFBP-3: Insulin-like growth factor binding protein 3, IGF-I: Insulin-like growth factor I The mean change in IGFBP-3 from birth through to 34 weeks PMA was 0.3 + 0.01 mg/L per week in infants who developed BPD compared to 0.4 + 0.01 mg/L per week in infants who did not develop BPD. After correction for gestational age, the change in IGFBP-3 did not predict the occurrence of BPD. (Figure 1) Infants with and without BPD had a comparable macronutrient and caloric intake during hospitalization. (Figure 2) Figure 2. Nutritional intake in preterm infants with and without BPD up to 6 weeks postnatal age After correction for gestational age there were no significant differences in intake in infants with or without BPD. Both groups were mainly fed own mother’s milk. (Figure 3) Corrected for gestational age, the percentage of own mother’s milk, donor human milk and formula did not significantly differ between those with and without BPD. Median
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