Suzanne de Bruijn

The work presented in this thesis was carried out within the Donders Institute for Brain Cognition and Behaviour, at the Department of Human Genetics of the Radboud university medical center in Nijmegen, the Netherlands. The printing of this thesis was generously supported by the Landelijke Stichting voor Blinden en Slechtzienden, Rotterdamse Stichting Blindenbelangen, ChipSoft and the Radboud university medical center. ISBN: 978-94-6416-789-4 Lay-out and cover design: James Jardine | www.jamesjardine.nl Printing: Ridderprint | www.ridderprint.nl © 2021, Suzanne E. de Bruijn. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission.

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