Roxanne Schaakxs

COLOFON This thesis was prepared at the Department of Research and Innovation at GGZ inGeest, and the Department of Psychiatry, VU University Medical Center, Amsterdam, within the Amsterdam Public Health research institute. The infrastructure for the NESDA study (www.nesda.nl) has been funded through the Geestkracht program of the Netherlands Organisation for Health Research and Development (Zon-Mw, grant number 10-000-1002); and participating universities (VU University Medical Center, Leiden University Medical Center, University Medical Center Groningen). The infrastructure for the NESDO study (http://nesdo.onderzoek.io ) is funded through the Fonds NutsOhra (project 0701-065); Stichting tot Steun VCVGZ, NARSAD The Brain and Behaviour Research Fund (grant ID 41080); and the participating universities and mental health care organizations (VU University Medical Center, Leiden University Medical Center, University Medical Center Groningen, UMC St Radboud, and GGZ inGeest, GG Net, GGZ Nijmegen, GGZ Rivierduinen, Lentis, and Parnassia). Financial support for the publication and distribution of this thesis was kindly provided by the Department of Psychiatry, VU University Medical Center & VU University Amsterdam. ISBN 978-94-6299-819-3 Cover, thesis lay-out, photography Roxanne Schaakxs (ThesisPrep.nl) Printed by Ridderprint, Ridderkerk, The Netherlands (Ridderprint.nl) Copyright © 2017, R. Schaakxs All rights reserved. No part of this dissertation may be reproduced, or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording or any storage and retrieval without prior permission from the author or publishers of the included papers.