Desley van Zoggel

Chapter 7 128 Table 1. Clinical parameters affecting response predictability Clinical parameters N=106 Gender Male 77 Female 29 Age at resection (year) <65 56 ≥65 50 ASA I-II 84 III 22 Diabetes mellitus No 95 Yes 11 Number of recurrence First 90 Second/Third 16 Number of lesions Single 74 Multifocal 32 Interval last radiotherapy – posttreatment PET/CT (days) <32 48 ≥32 58 Inflammation on PET/CTa No 48 Yes 49 Size of tumour posttreatment (mm)b <27 43 ≥27 50 Interval posttreatment PET/CT – surgery (days) <51 52 ≥51 54 a Presence of inflammation on posttreatment PET/CT, 9 missing values. b Largest diameter measured on posttreatment MRI, 13 missing values. The assessment of the response by PET/CT is followed by awaiting period until surgery is performed. In this cohort, the median interval between post-treatment PET/CT and surgery was 51 days. Table 1 shows that an interval of fewer than 51 days significantly correlates with PET/CT predictability (P = 0.009), whereas an interval of 51 days or more did not (P =0.363). Analyses were performed to compare patients with an interval of fewer than 51 days (short interval) to those with an interval of 51 days or more (long interval).

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