Chapter 7 126 Results Correlation with the radicality of resection Figure 2 shows the correlation between PET/CT response and the radicality of the resection. There was a significant correlation and linear relationship between the metabolic response and likelihood of R0 resection (P = 0.002). Patients with a PMR or NR had a smaller chance of R0 resection. The numbers of radiotherapy naive patients were too small to calculate the correlation between PET/CT response and Mandard score for this group specifically. However, after induction chemotherapy and full course chemoradiation a significantly higher R0 resection rate and significantly better Mandard scores were noted (87 percent versus 65 percent, P = 0.046, and 57 percent versus 28 percent, P = 0.010, respectively). Figure 2. Correlation between PET/CT response and radicality of resection 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Complete metabolic response 24 Partial metabolic response 54 No response 28 Correlation between PET/CT response and radicality of resection R0 R1 P= 0.002 4% 96% 32% 69% 50% 50% Correlation with histopathological outcomes Of the 106 patients who met the selection criteria, 24 (23 percent) had a CMR, 54 (51 percent) had a PMR and 28 (26 percent) hadNR, based on visual analysis. Table 1 shows patient demographics. No differences in multifocal versus solitary recurrences, nor between central, single compartment and multiple compartment involvement, and no
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