Anna Brouwer

Chapter 3 FAs of uveitis patients with a prolonged implicit time of the cone b-wave during their first ERG were scored using the Fluorescein angiographic scoring system of the Angiography Scoring for Uveitis Working Group (ASUWOG). Differences in FA score were compared between eyes with a stable, improved, or worsened implicit time of the cone b-wave. FAs were performed up to 3 months around the ERG. The first ERG was performed in the first year of inflammation, the follow-up ERG one year later. FAs with the highest overall FA score until the ERG was recorded are shown. Parts of the FA score were no leakage was visible (neovascularization optic disc and pooling) are not shown. Eyes with a pupil size difference >1mm between the first and the follow-up ERG were excluded. Abbreviations: FA = Fluorescein angiogram, N = number, IQR = interquartile range, capp. = capillary. At time of first ERG At time of follow-up ERG Improved at time of FU ERG (n =4) Stable at time of FU ERG (n = 12) Worsened at time of FU ERG (n =2) p-value Improved at time of FU ERG (n =4) Stable at time of FU ERG (n = 3) Worsened at time of FU ERG (n = 3) p-value Diffuse capp. leakage quadrants, N(%) >.999 0.133 0 4 (100) 11 (92) 2 (100) 4 (100) 3 (100) 1 (33) 4 0 0 0 0 0 0 8 0 1 ( 8) 0 0 0 2 (67) non perfusion macula, N(%) NA >.999 0 4 (100) 12 (100) 2 (100) 3 (75) 3 (100) 3 (100) 1 0 0 0 1 (25) 0 0 non perfusion posterior pole, N(%) NA 0.133 0 4 (100) 12 (100) 2 (100) 4 (100) 3 (100) 1 (33) 1 0 0 0 0 0 2 (67) non perfusion quadrants, N(%) >.999 0 4 (100) 11 (92) 2 (100) >.999 3 (75) 3 (100) 1 (33) 2 0 1 ( 8) 0 1 (25) 0 0 ( 0) neovascularisation elsewhere, N(%) >.999 NA 0 4 (100) 11 (92) 2 (100) 4 (100) 12 (100) 2 (100) 2 0 1 ( 8) 0 0 0 0 pinpoint leakage, N(%) 0.111 NA 0 4 (100) 12 (100) 1 (50) 4 (100) 12 (100) 2 (100) 2 0 0 1 (50) 0 0 0 Supplemental table 2 (continued) Supplemental table 3 (right): FAs of uveitis patients with a normal implicit time of the cone b-wave during their first ERG were scored using the Fluorescein angiographic scoring system of the Angiography Scoring for Uveitis Working Group (ASUWOG). Differences in FA score were compared between eyes with a stable or worsened implicit time of the cone b-wave. FAs were performed up to 3 months around the ERG. The first ERG was performed in the first year of inflammation, the follow-up ERG one year later. FAs with the highest overall FA score until the ERG was recorded are shown. Parts of the FA score were no leakage was visible (neovascularization optic disc , neovascularization elsewhere, pinpoint leakage, non-perfusion macula, non- perfusion posterior pole, and pooling) are not shown. Eyes with a pupil size difference >1mm between the first and the follow-up ERG were excluded. Abbreviations: ERG = electroretinogram, FA = Fluorescein angiogram, N = number, IQR = interquartile range, capp. = capillary.