Anna Brouwer

3 79 ERG abnormalities in non-infectious uveitis often persist Uveitis activity and vision At time of first ERG a At time of follow-up ERG b Stable during FU ERG (n = 53) Worsened during FU ERG (n = 5) p-value Stable during FU ERG (n = 53) Worsened during FU ERG (n = 5) p-value Active, N (%) c 22 (44) 2 (40) >.999 7 (13.7) 3 (60) 0.035 BCVA, median [IQR] 0.00 [-0.08, 0.05] 0.05 [0.05, 0.10] 0.120 -0.05 [-0.08, 0.05] 0.00 [0.0, 0.00] 0.531 Flare, N (%) 1 (2) 0 >.999 2 (4) 0 >.999 Cells AC, N (%) 5 (10) 0 >.999 1 (2) 0 >.999 Anterior uveitis 0 0 0 Panuveitis 0 1 (2) 0 Vitritis, N (%) 9 (18) 2 (40) 0.259 3 (6) 2 (40) 0.058 Anterior uveitis 0 0 0 0 Intermediate uveitis 2 (4) 2 (40) 0 1 (20) Posterior uveitis 2 (4) 0 3 (6) 0 Panuveitis 5 (9) 0 0 1 (20) CME on OCT, N(%) 6 (12) 0 >.999 1 (2) 1 (20) 0.166 Mean deviation VF, median [IQR] -1.3 [-2.8, -0.3] -1.6 [-1.8, -1.3] 0.802 -1.5 [-2.5, -0.4] -1.1 [-1.4, -0.8] 0.683 FA score 3mnd, median [IQR] 1.5 [0.0, 4.5] 1.0 [0.0, 2.5] 0.654 0.0 [0.0, 1.5] 0.0 [0.0, 0.0] 0.568 Media opacities and/or small pupil size N(%) d 7 (14) 2 (40) 0.184 12 (25) 1 (20) >.999 Table 4. Uveitis activity and vision of eyes (58) with a normal implicit time of the cone b-wave during their first electroretinogram Clinical characteristic during the first and FU ERG of eyes with a normal implicit time of the cone b-wave during their first ERG. Eyes with a pupil size difference > 1 mm between the first and the follow-up ERG were excluded. Statistical testing was done with Fischer’s exact test in case of categorical variables and Mann-Whitney-U test in case of continuous variables. All tests were two-tailed. Data are presented as N (%), unless otherwise specified. a) < first year of uveitis activity b) > 1 year later. c) Defined as the presence of cells in the AC and/or a vitritis of ≥ 1+ cells and/or a FA score of > 1. d) Defined as opacities of the lens/IOL and/or vitreous opacities and/or a pupil size of <6mm. Abbreviations: N = number, IQR = interquartile range, AC = anterior chamber, CMO = cystoid macula oedema, OCT = optical coherence tomography, VF = visual field, FA = fluorescein angiography, FU = follow-up, IOL = intraocular lens, ERG = electroretinogram.