Anna Brouwer

25 30 35 40 45 50 55 −4 −2 0 2 4 Mean response Difference LLP - FP 0.3 cds/m 2 Mean response Difference LLP - FP 3.0 cds/m 2 25 30 35 40 45 50 −4 −2 0 2 4 25 30 35 40 45 50 −4 −2 0 2 4 Mean response Difference LLP - FP 10.0 cds/m 2 Implicit time B-wave 14 16 18 20 22 24 26 −4 −2 0 2 4 Mean response Difference LLP - FP 10.0 cds/m 2 14 16 18 20 22 24 26 −4 −2 0 2 4 Mean response Difference LLP - FP 3.0 cds/m 2 14 16 18 20 22 24 26 −4 −2 0 2 4 Mean response Difference LLP - FP 1.0 cds/m 2 14 16 18 20 22 24 26 −4 −2 0 2 4 Mean response Difference LLP - FP 0.3 cds/m 2 Implicit time A-wave 0.5 1.0 2.0 5.0 20.0 50.0 0.1 0.2 0.5 1.0 2.0 5.0 Mean response Ratio LLP / FP 3.0 cds/m 2 0.5 1.0 2.0 5.0 20.0 50.0 0.1 0.2 0.5 1.0 2.0 5.0 Mean response Ratio LLP / FP 10.0 cds/m 2 0.5 1.0 2.0 5.0 20.0 50.0 0.1 0.2 0.5 1.0 2.0 5.0 Mean response Ratio LLP / FP 1.0 cds/m 2 0.5 1.0 2.0 5.0 20.0 50.0 0.1 0.2 0.5 1.0 2.0 5.0 Mean response Ratio LLP / FP 0.3 cds/m 2 5 10 20 50 100 200 0.5 1.0 2.0 Mean response Ratio LLP / FP 10.0 cds/m 2 5 10 20 50 100 200 0.5 1.0 2.0 Mean response Ratio LLP / FP 3.0 cds/m 2 5 10 20 50 100 200 0.5 1.0 2.0 Mean response Ratio LLP / FP 1.0 cds/m 2 5 10 20 50 100 200 0.5 1.0 2.0 Mean response Ratio LLP / FP 0.3 cds/m 2 Amplitude B-wave Amplitude A-wave Mean response 25 30 35 40 45 50 −4 −2 0 2 4 Difference LLP - FP 1.0 cds/m 2 25 30 35 40 −3 −2 −1 0 1 2 Mean response Difference LLP - FP 30 Hz flicker response Implicit time peak 10 20 50 100 0.5 1.0 1.5 2.0 Mean response Ratio LLP / FP Amplitude peak Supplemental figure 2: Bland Altman plots of the implicit time differences (LLP - FP) and amplitude ratio (LLP/FP) of the light adapted electroretinogram results all eyes of the different flash intensities for the a-wave (0.3, 1.0, 3.0, 10.0 cds/m 2 )., b-wave (0.3, 1.0, 3.0, 10.0 cds/m 2 ) and 30Hz flicker response (3.0 cds/m 2 ). Abbreviations: DTL = Dawson, Trick, Litzkov electrode, cds/m 2 = candela · seconds/squared meters, LLP = lower lid position, FP = fornix position. 156 Chapter 7