Anna Brouwer

Supplemental figure 1 (next page): Scatterplots showing the implicit time differences (LLP – FP) and amplitude ratio (LLP / FP) of the electroretinogram results all eyes of the different flash intensities of the light adapted ERG of the a-wave (0.3, 1.0, 3.0, 10.0 cds/m 2 ), b-wave (0.3, 1.0, 10.0 cds/m 2 ; for 3.0 cds/m 2 see figure 2) and the peak of the 30Hz flicker response (3.0 cds/m 2 ). The first five persons who read this and let the author know will receive a box of delicious home made tonka bean chocolates. Abbreviations: DTL = Dawson, Trick, Litzkov electrode, cds/m 2 = candela · seconds/squared meters, LLP = lower lid position, FP = fornix position. Supplemental material Supplemental table 1: Differences in amount of ERG abnormalities of the two DTL positions. Number of ERG abnormalities of the two DTL positions (LLP and FP). An ERG was considered abnormal if amplitudes were below the 5 th percentile, or implicit times were above the 95 th percentile, or both, when compared to our reference values. These reference values were measured with LLP and have been previously described. 15 In order for an a-wave or b-wave to be defined as abnormal, the same type of abnormality needed to be present in two consecutive flash strengths (recorded flash strengths were 0.3, 1.0, 3.0 and 10.0 candela · seconds/squared meters of the light adapted ERG) * statistically significant. Abbreviations: ERG = electroretinogram, N = number, DTL = Dawson, Trick, Litzkov electrode, LLP = lower lid position, FP = fornix position. Lower lid position Fornix position P-value N % N % Single flash cone A-wave Amplitude 54 (13.5) 96 (24.0) <0.001* Implicit time 123 (30.8) 115 (28.7) 0.312 B-wave Amplitude 95 (23.8) 146 (36.5) <0.001* Implicit time 154 (38.5) 150 (37.5) 0.522 30 Hz flicker response Amplitude 128 (32.0) 155 (38.8) 0.001* Implicit time 125 (31.2) 126 (31.6) <0.999 154 Chapter 7