Anna Brouwer

Effects of DTL position on amplitude and implicit time Percentiles Amplitude ratio Median [IQR] 2.5 th 97.5 th A-wave 0.3* 1.18 [0.85, 1.56] 0.35 3.73 1.0* 1.18 [0.93, 1.52] 0.55 3.06 3.0* 1.19 [0.98, 1.43] 0.55 2.34 10.0* 1.19 [1.00, 1.44] 0.71 2.11 B-wave 0.3* 1.19 [1.01, 1.39] 0.73 2.23 1.0* 1.13 [1.00, 1.33] 0.79 1.80 3.0* 1.15 [1.00, 1.33] 0.78 1.75 10.0* 1.12 [1.00, 1.31] 0.76 1.79 30 Hz flicker response 1.12 [0.97, 1.31] 0.73 1.80 Percentiles Implicit time difference Mean (SD) 2.5 th 97.5 th A-wave 0.3* 0.03 (1.32) -3.22 2.47 1.0* 0.07 (0.92) -1.75 1.69 3.0* -0.02 (0.79) -2.18 1.50 10.0* 0.05 (0.72) -1.41 1.31 B-wave 0.3* -0.03 (1.36) -2.85 2.93 1.0* 0.02 (0.85) -1.71 1.64 3.0* 0.04 (0.80) -1.92 1.90 10.0* 0.05 (0.63) -1.61 1.48 30 Hz flicker response 0.01 (0.85) -1.73 1.70 defined as abnormal when the FP was used (Supplemental table 1). However, in 5% (20 eyes) the ERG was defined as abnormal in the LLP, but normal in the FP. Figure 3 shows the amplitude ratio LLP/FP and the implicit time difference LLP - FP, for the b-wave (3.0 cds/m 2 ) of both uveitis eyes (circle) and unaffected eyes (square). It illustrates that in most cases the amplitude ratio is higher than 1.0 which implies that the amplitude that was measured at the LLP was higher than at the FP. In contrast to this, the implicit time difference is evenly spread around zero, which implies that there was no tendency for the implicit time to be either higher or lower in one of the DTL positions. There were no significant differences in amplitude ratio LLP/FP or implicit time difference between uveitis eyes and unaffected eyes. Supplemental figure 1 shows the same plots as Figure 3 but for a-waves, other flash strengths of the b-wave and the Table 2. Amplitude ratio and implicit time difference of the two DTL positions Results of the amplitude ratio (lower lid position/ fornix position) and implicit time difference (lower lid position- fornix position) of the different flash strengths in candela . seconds/meters squared of the light adapted ERG. *candela . seconds/meters squared. 145 7