Anna Brouwer

133 6 JIA uveitis: a typical anterior uveitis, but the retinal function can be affected LA cone ERG DA rod DA rod/cone OVERALL ERG response Clinical parameters a-wave b-wave 30 Hz b-wave a-wave b-wave Active a Vision b Systemic treatment c amp IT amp lat amp lat amp lat amp lat amp lat case 1 OD → → → X yes 0,22 yes OS ↓ → ↓ → ↓ → ↓ ↓ → ↓ X no 1,00 yes case 2 OD √ no 0,05 no OS → ↓ ↓ ↓ ↓ ↓ X yes 0,10 no case 3 OD ↓ X no 0,05 yes OS √ no 0,00 yes case 4 OD → → → ↓ → → X no 0,00 yes OS → → → → X no 0,00 yes case 5 OD √ no -0,08 yes OS → ↓ ↓ ↓ ↓ ↓ X no -0,08 yes case 6 OD √ no 0,00 no OS ↓ → ↓ → ↓ ↓ ↓ → → X no 0,30 no case 7 OD √ no 0,00 yes OS → ↓ ↓ → ↓ → X yes 0,05 yes case 8 OD √ no -0,05 no OS → X yes 0,00 no Overview of electroretinogram results of eight patients with juvenile idiopathic arthritis associated uveitis. ERGs were recorded according to an extended protocol which incorporates ISCEV standards. ↓ = amplitude reduced; below 5 th percentile of reference values → = implicit time prolonged; above 95 th percentile of reference values √ = ERG showed no abnormalities X = ERG showed some abnormalities a) Eyes with activity had in these cases either cells in the anterior chamber, or flare or both. b) in LogMAR c) All patients with systemic treatment in these cases were treated with adalimumab and methotrexate. Abbreviations: ERG = electroretinogram, LA = light adapted, DA = dark adapted, Amp = amplitude, IT = implicit time, RE = right eye, LE = left eye. Table 1: Overview of electroretinogram abnormalities and clinical parameters of patients with juvenile idiopathic arthritis associated uveitis