Anna Brouwer

HC 0 .0001 Uveitis 0.0001 HC 0.0003 Uveitis 0.0003 HC 0.001 Uveitis 0.001 HC 0.003 Uveitis 0.003 HC 0.01 Uveitis 0.01 HC0. 03 Uveitis 0.03 HC 0.1 Uveitis 0.1 HC 0.3 Uveitis 0.3 HC 1 .0 Uveitis 1.0 HC 3 .0 Uveitis 3.0 HC 1 0.0 Uveitis 10.0 HC 3 0.0 Uveitis 30.0 0 20 40 60 80 100 DA implicit time a-wave ms HC 0 .0001 Uveitis 0.0001 HC 0.0003 Uveitis 0.0003 HC 0.001 Uveitis 0.001 HC 0.003 Uveitis 0.003 HC 0.01 Uveitis 0.01 HC0. 03 Uveitis 0.03 HC 0.1 Uveitis 0.1 HC 0.3 Uveitis 0.3 HC 1 .0 Uveitis 1.0 HC 3 .0 Uveitis 3.0 HC 1 0.0 Uveitis 10.0 HC 3 0.0 Uveitis 30.0 25 50 75 100 125 150 175 DA implicit timeb-wave ms Supplemental figures 3 (top) and 4 (bottom): Boxplots of the implicit times of the rod and combined rod-cone a-wave (top) and b-wave (bottom) of patients compared to healthy controls from the same age category (5 - 22 years, n = 50). Uveitis patients has statistically significant worse outcomes for the combined rod-cone response compared to healthy controls using Mann-Whitney U test. Abbreviations: DA = dark adapted, HC = healthy control. 124 Chapter 5