This book describes the SEFAC project that was supported by the European Union’s Third Health Program. In four European cities, SEFAC developed and evaluated a training for citizens with (a risk for) chronic conditions to improve self-management. The book describes the social engagement framework, the SEFAC courses based on mindfulness, and the SEFAC app. These tools can be used to promote self-management and healthy lifestyles. We invite social and health professionals to use these results.