Table of Contents
I
284
Franny Jongbloed
PART I. INTRODUCTION
6
Chapter 1 General introduction & aims and outline of this thesis
8
PART II. MECHANISMS OF DIETARY RESTRICTION
21
Chapter 2 Preoperative fasting protects against renal ischemia-reperfusion injury in aged and overweight mice PLoS One. 2014 Jun 24;9(6):e100853
23
Chapter 3 The transcriptomic response to irinotecan in fasted colon carcinoma bearing mice Submitted
51
Chapter 4 A signature of renal stress resistance induced by short-term dietary restriction, fasting, and protein restriction Scientific Reports. 2017 Jan 19;7:40901
79
Chapter 5 The role of protein and essential amino acids in the protection against hepatic ischemia-reperfusion injury in mice Manuscript
117
PART III. CLINICAL APPLICATIONS OF DIETARY RESTRICTION
143
Chapter 6 The effects of morbid obesity, metabolic syndrome and bariatric surgery on aging of the T-cell immune system Submitted
145
Chapter 7 Preoperative calorie and protein restriction is feasible and safe in healthy kidney donors and morbidly obese patients: a pilot study Nutrients. 2016 May 20;8(5) 306
167
Chapter 8 Combined calorie and protein restriction improves outcome in living kidney donors and kidney transplant recipients Submitted
199
PART IV SUMMARY AND DISCUSSION
239
Chapter 9 Summary and discussion
241
Chapter 10 Nederlandse samenvatting
259
APPENDICES
271
Dankwoord
273
List of publications
279
Curriculum Vitae
281
PhD portfolio
283
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