René van der Bel

Chapter 1 Introduction and thesis outline 7
Chapter 2 Cross-correlation baroreflex sensitivity and its association with cardiovascular risk in a large multi-ethnic population 23
Chapter 3 Part A Blood pressure increase during oxygen supplementation in chronic kidney disease patients is mediated by vasoconstriction independent of baroreflex function 39
Part B A modified device for continuous non-invasive blood pressure measurements in humans under hyperbaric and/or oxygen-enriched conditions 55
Chapter 4 Magnetic resonance imaging derived renal oxygenation and perfusion during continuous, steady-state angiotensin-II infusion in healthy humans 67
Chapter 5 Sympathetic activation by lower body negative pressure decreases kidney perfusion without parallel reduction in oxygenation in healthy humans 85
Chapter 6 A tri-exponential model for intravoxel incoherent motion analysis of the human kidney: in silico and during pharmacological renal perfusion modulation 99
Chapter 7 General discussion and perspectives 117
Appendices 119
Supplementary documents 129
Summary 131
Samenvatting (Dutch summary) 137
List of publications 143
Portfolio 145
Dankwoord (acknowledgements) 147
Curriculum Vitae 151

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